Pegaso Vent

Pegaso Vent is a negative pressure ventilator and represents the primary and most traditional method of assisted long-term ventilation.

Pegaso Vent withdraws mechanically the air from a chamber, which embraces the chest (or the whole body) and as a consequence creates a sub-atmospheric pressure inside. This leads to an expansion of the chest, which causes a decrease in intrapulmonary pressure, and increases flow of ambient air into the lungs. When Pegaso Vent switches to positive pressure and forces air in the chamber, the chest will be compressed and the lungs will exhale. The exhalation can also be passive, through ambient instead of positive pressure, which often is sufficient to deflate the lungs.

This ventilation method reproduces mechanically ventilation similar to the human spontaneous breathing.

The following accessories can be connected to Pegaso Vent:

Even though this is a rather traditional ventilation system, today there is still an important role for negative pressure ventilation (NPV).

It is recommended to use NPV when patients have the following problems:

  • intolerance of facial mask (claustrophobia)
  • facial deformity
  • excessive airway secretion
  • respiratory distress syndrome of the newborn (treated with continuous negative pressure ventilation CNEP)
  • respiratory distress syndrome of children due to bronchiolitis
  • chronic respiratory failure in patients with chronic obstructive pulmonary disease and restrictive thoracic disorders

The many advantages of NPV compared to the invasive techniques, especially in the management of ICU settings, can be summarised as follows:

  • normal swallowing, feeding, speech are maintained
  • significant reduction of costs and risks related to invasive endotracheal intubation
  • shorter stays in ICU
  • less sedatives are necessary
  • general cost reduction of ICU management
  • weaning process of ventilated patients becomes easier and more natural

NPV continues to cover an important role for diagnostic and therapeutic surgeries carried out with the fibrebronchoscopy.

For all patients that use NPV at home on a longterm basis the following advantages can be highlighted:

  • greater comfort as an almost “natural” breathing is allowed
  • the possibility to eat, drink, talk and cough, even when mechanically ventilated

Studies and references


New non invasive ventilator strategy applied to COPD patients in acute ventilator failure 681.00 KB 51 downloads

Carpagnano GE, Sabato R, Lacedonia D, Di Gioia R, Saliani V, Vincenzi U, Foschino-Barbaro...

Iron lung versus mask ventilation in acute exacerbation of COPD, a randomised crossover study 281.53 KB 5 downloads

Corrado et al. Intensive Care Med, 648-655, 2009 ...

Negative Pressure Ventilation, Better Oxygenation and Less Lung Injury 148.55 KB 5 downloads

Grasso, Engelberts, etc., Am J Respir Crit Care Med, Vol 177. pp 412–418, 2008 ...

Respiratory support of infants with bronchiolitis related apnoea is there a role for negative pressure 63.76 KB 4 downloads

J Henderson, Arch Dis Child, 2005, 90: 224-225 ...

Treatment of Acute Exacerbations of Chronic Respiratory Failure 452.58 KB 5 downloads

Todisco, Baglioni, etc Chest 2004;125;2217-2223 ...

Physiologic Effects of Negative Pressure Ventilation in Acute Exacerbation of COPD 76.10 KB 3 downloads

Gorini, Corrado. Am J Respir Crit Care Med Vol 163. pp 1614–1618, 2001 ...

Continuous negative extra thoracic pressure in neonatal respiratory failure 178.91 KB 3 downloads

Samuels, Raine, Wright. Pediatrics 1996; 98:1154-1160 ...

Negative-pressure ventilation is there still a role? 136.45 KB 5 downloads

A. Corrado, M. Gorini, Eur Respir J, 2002; 20: 187–197 ...

Negative pressure ventilation in the treatment of acute respiratory failure. an old noninvasive technique reconsidered 302.80 KB 3 downloads

A. Corrado, M. Gorini, G. Villella, E. De Paola; Eur Respir J, 1996; 9, 1531–1544 ...

Negative pressure ventilation in pediatric critical care setting 110.84 KB 3 downloads

Akash Deep, Claudine De Munter, Ajay Desai; Indian Journal of Pediatrics, 2007; 74...


    May you have question or wish to share your experience with this device, please leave a comment below:

    Leave a Reply

    Your email address will not be published. Required fields are marked *